MolNFT v1 · #169996 · protein

Subunit bbs 5 of the human core bbsome complex

6XTB · Bardet-biedl syndrome 5 protein: “Subunit bbs 5 of the human core bbsome complex”. Electron microscopy, 4 pockets (best druggability 0.75). MolNFT v1 #169996 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6XTB
Type: protein
Length: 235 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Bardet-biedl syndrome 5 protein
UniProt: Q8N3I7
Pockets: 4 · best druggability 0.75

Structure

electron microscopy · 1 distinct chain · 10% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
E	Bardet-biedl syndrome 5 protein	protein	235	10% helix, 31% strand	Q8N3I7

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1057	0.75	0.78	77	empty
2	655	0.68	0.77	67	empty
3	210	0.49	0.75	37	empty
4	89	0.32	0.73	25	empty

Compared structures

6XTB · Subunit BBS 5 of the human core BBSome complex · the same entry in another collection · chain E against E, TM-score 1.00
Q8N3I7 · AlphaFold monomer V2.0 prediction for bardet-biedl syndrome 5 protein (Q8N3I7) · a predicted model of the same protein · chain E against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N3I7
Elsewhere: RCSB PDB 6XTB · PDBe 6XTB · UniProt Q8N3I7

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