MolNFT v1 · #16996 · protein

Nucleosome recognition module of iswi ATPase

1OFC · Iswi protein: “Nucleosome recognition module of iswi ATPase”. X-ray diffraction, 2 ligands (G4D, GLC), 1 pocket (best druggability 0.33). MolNFT v1 #16996 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1OFC
Type: protein
Length: 266 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Iswi protein
UniProt: Q24368
Ligands: G4D, GLC
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 66% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Iswi protein	protein	266	66% helix, 0% strand	Q24368

Ligands and binding sites

G4D · 4-deoxy-alpha-D-glucopyranose · ligand · chains X
GLC · alpha-D-glucopyranose · sugar · chains X
GOL · Glycerol · additive · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.33	0.75	17	empty

Compared structures

1OFC · nucleosome recognition module of ISWI ATPase · the same entry in another collection · chain X against X, TM-score 1.00
Q24368 · AlphaFold monomer V2.0 prediction for chromatin-remodeling complex ATPase chain iswi… · a predicted model of the same protein · chain X against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q24368
Elsewhere: RCSB PDB 1OFC · PDBe 1OFC · UniProt Q24368

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