MolNFT v1 · #169904 · protein
Structure of HIV-1 vpr in complex with the human nucleotide excision repair protein HHR23A
6XQJ · Protein VPR,UV excision repair protein RAD23 homolog a: “Structure of HIV-1 vpr in complex with the human nucleotide excision repair protein HHR23A”. Solution nmr, 1 ligand (ZN), 2 pockets (best druggability 0.42). MolNFT v1 #169904…
- PDB
- 6XQJ
- Type
- protein
- Length
- 173 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein VPR,UV excision repair protein RAD23 homolog a
- UniProt
- P12520, P54725
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.42
Structure
solution nmr · 1 distinct chain · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein VPR,UV excision repair protein RAD23 homolog a | protein | 173 | 76% helix, 0% strand | P12520, P54725 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 169 | 0.42 | 0.73 | 28 | empty |
| 2 | 70 | 0.36 | 0.77 | 12 | empty |
Compared structures
- 6XQJ · Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A · the same entry in another collection · chain A against A, TM-score 1.00
- P54725 · AlphaFold monomer V2.0 prediction for UV excision repair protein RAD23 homolog a (P54725) · a predicted model of the same protein · chain A against A, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12520
- Every structure of UniProt P54725
- Elsewhere: RCSB PDB 6XQJ · PDBe 6XQJ · UniProt P12520 · UniProt P54725
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