MolNFT v1 · #169681 · protein
Biuret hydrolase (biuh) from rhodococcus sp. mel C169S apo form
6XK1: “Biuret hydrolase (biuh) from rhodococcus sp. mel C169S apo form”. X-ray diffraction, 5 pockets (best druggability 0.87). MolNFT v1 #169681 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6XK1
- Type
- protein
- Length
- 911 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Biuret hydrolase
- UniProt
- H8ZKV9
- Pockets
- 5 · best druggability 0.87
Structure
x-ray diffraction · 4 distinct chains · 39% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Biuret hydrolase | protein | 226 | 38% helix, 22% strand | H8ZKV9 |
| B | Biuret hydrolase | protein | 227 | 39% helix, 22% strand | H8ZKV9 |
| C | Biuret hydrolase | protein | 228 | 39% helix, 22% strand | H8ZKV9 |
| D | Biuret hydrolase | protein | 230 | 38% helix, 22% strand | H8ZKV9 |
Pockets
5 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 565 | 0.87 | 0.93 | 56 | empty |
| 2 | 309 | 0.63 | 0.80 | 35 | empty |
| 3 | 298 | 0.62 | 0.79 | 34 | empty |
| 4 | 309 | 0.60 | 0.78 | 32 | empty |
| 5 | 304 | 0.59 | 0.78 | 34 | empty |
Interfaces
6 interfaces between chains.
- A–D · 2024 Ų buried · 34 hydrogen bonds · protein-protein
- B–C · 2012 Ų buried · 36 hydrogen bonds · protein-protein
- A–B · 872 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 869 Ų buried · 10 hydrogen bonds · protein-protein
- A–C · 233 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 6XK1 · Biuret Hydrolase (BiuH) from Rhodococcus sp. Mel C169S Apo form · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt H8ZKV9
- Elsewhere: RCSB PDB 6XK1 · PDBe 6XK1 · UniProt H8ZKV9
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