MolNFT v1 · #16962 · protein
MONA/GADS SH3C domain
1OEB · GRB2-related adaptor protein 2: “MONA/GADS SH3C domain”. X-ray diffraction, 1 ligand (CD). MolNFT v1 #16962 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1OEB
- Type
- protein
- Length
- 138 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GRB2-related adaptor protein 2; Lymphocyte cytosolic protein 2
- UniProt
- O89100, Q60787
- Ligands
- CD
Structure
x-ray diffraction · 3 distinct chains · 7% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GRB2-related adaptor protein 2 | protein | 59 | 5% helix, 46% strand | O89100 |
| B | GRB2-related adaptor protein 2 | protein | 55 | 5% helix, 49% strand | O89100 |
| C, D | Lymphocyte cytosolic protein 2 | protein | 12 | 25% helix, 0% strand | Q60787 |
Ligands and binding sites
- CD · Cadmium ion · metal · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
3 interfaces between chains.
- B–C · 610 Ų buried · 8 hydrogen bonds · protein-protein
- A–D · 605 Ų buried · 10 hydrogen bonds · protein-protein
- A–B · 421 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 1OEB · Mona/Gads SH3C domain · the same entry in another collection · chain A against A, TM-score 1.00
- O89100 · AlphaFold monomer V2.0 prediction for GRB2-related adaptor protein 2 (O89100) · a predicted model of the same protein · chain B against A, TM-score 0.96
- Q60787 · AlphaFold monomer V2.0 prediction for lymphocyte cytosolic protein 2 (Q60787) · a predicted model of the same protein · chain C against A, TM-score 0.32
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O89100
- Every structure of UniProt Q60787
- Elsewhere: RCSB PDB 1OEB · PDBe 1OEB · UniProt O89100 · UniProt Q60787
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