MolNFT v1 · #169088 · protein
Crystal structure of thioredoxin natrxh from nicotiana alata
6X0B · Thioredoxin H: “Crystal structure of thioredoxin natrxh from nicotiana alata”. X-ray diffraction, 1 pocket (best druggability 0.32). MolNFT v1 #169088 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6X0B
- Type
- protein
- Length
- 231 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thioredoxin H
- UniProt
- Q4U0W0
- Pockets
- 1 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thioredoxin H | protein | 116 | 37% helix, 25% strand | Q4U0W0 |
| B | Thioredoxin H | protein | 115 | 38% helix, 24% strand | Q4U0W0 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 78 | 0.32 | 0.74 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 595 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 6X0B · Crystal Structure of Thioredoxin NaTrxh from Nicotiana alata · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4U0W0
- Elsewhere: RCSB PDB 6X0B · PDBe 6X0B · UniProt Q4U0W0
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