MolNFT v1 · #169007 · protein
Crystal structure of apo CARD1
6WXW: “Crystal structure of apo CARD1”. X-ray diffraction, 6 pockets (best druggability 0.60). MolNFT v1 #169007 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WXW
- Type
- protein
- Length
- 744 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CARD1
- UniProt
- F2NWD3
- Pockets
- 6 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | CARD1 | protein | 372 | 44% helix, 21% strand | F2NWD3 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 486 | 0.60 | 0.74 | 55 | empty |
| 2 | 297 | 0.55 | 0.76 | 41 | empty |
| 3 | 237 | 0.50 | 0.75 | 38 | empty |
| 4 | 131 | 0.38 | 0.73 | 27 | empty |
| 5 | 50 | 0.31 | 0.77 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1586 Ų buried · 29 hydrogen bonds · protein-protein
Compared structures
- 6WXW · crystal structure of apo Card1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F2NWD3
- Elsewhere: RCSB PDB 6WXW · PDBe 6WXW · UniProt F2NWD3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.