MolNFT v1 · #168992 · protein
Crystal structure of NSP15 endoribonuclease from SARS cov-2 in the complex with potential repurposing drug tipiracil
6WXC: “Crystal structure of NSP15 endoribonuclease from SARS cov-2 in the complex with potential repurposing drug…”. X-ray diffraction, 2 ligands (CMU, PO4). MolNFT v1 #168992 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WXC
- Type
- protein
- Length
- 695 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0DTD1
- Ligands
- CMU, PO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 348 | — | P0DTD1 |
| B | — | protein | 347 | — | P0DTD1 |
Ligands and binding sites
- CMU · 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl) uracil · ligand · 2 copies · chains A, B
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 9 copies · chains A, B
- FMT · Formic acid · additive · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6WXC · Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with potential… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DTD1
- Elsewhere: RCSB PDB 6WXC · PDBe 6WXC · UniProt P0DTD1
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