MolNFT v1 · #168946 · protein
Crystal structure of anti-met Fab arm of amivantamab in complex with human met
6WVZ: “Crystal structure of anti-met Fab arm of amivantamab in complex with human met”. X-ray diffraction, 2 ligands (NAG, FUC). MolNFT v1 #168946 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WVZ
- Type
- protein
- Length
- 946 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P08581
- Ligands
- NAG, FUC
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| H | — | protein | 215 | — | — |
| L | — | protein | 213 | — | — |
| M | — | protein | 518 | — | P08581 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains M
- FUC · alpha-L-fucopyranose · sugar · 2 copies · chains M
- FMT · Formic acid · additive · chains M
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6WVZ · Crystal structure of anti-MET Fab arm of amivantamab in complex with human MET · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08581
- Elsewhere: RCSB PDB 6WVZ · PDBe 6WVZ · UniProt P08581
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.