MolNFT v1 · #168898 · protein
Mitochondrial SAM complex - monomer in detergent
6WUJ · SAM35: “Mitochondrial SAM complex - monomer in detergent”. Electron microscopy, 10 pockets (best druggability 0.75). MolNFT v1 #168898 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WUJ
- Type
- protein
- Length
- 884 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SAM35; BAC_SURFACE_AG domain-containing protein; TOM37 domain-containing protein
- UniProt
- G2QAT9, G2QFF9, G2Q6R7
- Pockets
- 10 · best druggability 0.75
Structure
electron microscopy · 3 distinct chains · 32% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SAM35 | protein | 282 | 43% helix, 5% strand | G2QAT9 |
| B | BAC_SURFACE_AG domain-containing protein | protein | 318 | 5% helix, 34% strand | G2QFF9 |
| C | TOM37 domain-containing protein | protein | 284 | 51% helix, 4% strand | G2Q6R7 |
Pockets
10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1054 | 0.75 | 0.78 | 99 | empty |
| 2 | 79 | 0.73 | 0.96 | 21 | empty |
| 3 | 231 | 0.68 | 0.85 | 31 | empty |
| 4 | 178 | 0.66 | 0.86 | 36 | empty |
| 5 | 577 | 0.65 | 0.76 | 66 | empty |
Interfaces
2 interfaces between chains.
- A–B · 1722 Ų buried · 17 hydrogen bonds · protein-protein
- A–C · 1676 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 6WUJ · Mitochondrial SAM complex - monomer in detergent · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G2QAT9
- Every structure of UniProt G2QFF9
- Every structure of UniProt G2Q6R7
- Elsewhere: RCSB PDB 6WUJ · PDBe 6WUJ · UniProt G2QAT9 · UniProt G2QFF9 · UniProt G2Q6R7
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