MolNFT v1 · #168824 · protein

Crystal structure of eutv from enterococcus faecalis

6WSH · Response regulator: “Crystal structure of eutv from enterococcus faecalis”. X-ray diffraction, 2 ligands (NA, MG), 3 pockets (best druggability 0.57). MolNFT v1 #168824 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6WSH
Type: protein
Length: 380 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Response regulator
UniProt: A0A1Q1FU69
Ligands: NA, MG
Pockets: 3 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Response regulator	protein	190	62% helix, 13% strand	A0A1Q1FU69

Ligands and binding sites

NA · Sodium ion · metal · 11 copies · chains A, B
MG · Magnesium ion · metal · 2 copies · chains A, B
GOL · Glycerol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	99	0.57	0.86	22	NA
2	202	0.50	0.76	23	NA
3	85	0.49	0.82	18	GOL

Interfaces

1 interface between chains.

A–B · 1967 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

6WSH · Crystal structure of EutV from Enterococcus faecalis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1Q1FU69
Elsewhere: RCSB PDB 6WSH · PDBe 6WSH · UniProt A0A1Q1FU69

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.