MolNFT v1 · #168337 · protein

Crystal structure of laccase from thermus thermophilus HB27 with an open conformation of beta-hairpin (average deposited dose 20.67 mgy)

6WCP: “Crystal structure of laccase from thermus thermophilus HB27 with an open conformation of beta-hairpin…”. X-ray diffraction, 1 ligand (CU), 4 pockets (best druggability 0.57). MolNFT v1 #168337 on GenesisL1: 3D structure, binding…

PDB: 6WCP
Type: protein
Length: 440 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Laccase
EC: 1.10.3.2
UniProt: Q72HW2
Ligands: CU
Pockets: 4 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Laccase (EC 1.10.3.2)	protein	440	6% helix, 47% strand	Q72HW2

Ligands and binding sites

CU · Copper (II) ion · metal · 2 copies · chains A
GOL · Glycerol · additive · chains A
1PE · Pentaethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	239	0.57	0.78	23	1PE
2	162	0.49	0.77	32	empty
3	96	0.36	0.75	21	empty
4	50	0.28	0.75	15	empty

Compared structures

6WCP · Crystal structure of Laccase from Thermus thermophilus HB27 with an open conformation of… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72HW2
Elsewhere: RCSB PDB 6WCP · PDBe 6WCP · UniProt Q72HW2

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