MolNFT v1 · #168243 · protein
De novo designed receptor transmembrane domains enhance car-T cytotoxicity and attenuate cytokine release
6W9Z: “De novo designed receptor transmembrane domains enhance car-T cytotoxicity and attenuate cytokine release”. X-ray diffraction, 1 ligand (OLB). MolNFT v1 #168243 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6W9Z
- Type
- protein
- Length
- 173 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Ligands
- OLB
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, E | — | protein | 29 | — | — |
| D | — | protein | 30 | — | — |
| F | — | protein | 27 | — | — |
Ligands and binding sites
- OLB · (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · ligand · 2 copies · chains A, B, F, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6W9Z · De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6W9Z · PDBe 6W9Z
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