MolNFT v1 · #168240 · protein

R80A PCNA mutant defective in bir

6W9W · Proliferating cell nuclear antigen: “R80A PCNA mutant defective in bir”. X-ray diffraction, 3 pockets (best druggability 0.43). MolNFT v1 #168240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6W9W
Type: protein
Length: 256 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proliferating cell nuclear antigen
UniProt: P15873
Pockets: 3 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 19% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proliferating cell nuclear antigen	protein	256	19% helix, 46% strand	P15873

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	99	0.43	0.78	17	empty
2	59	0.36	0.78	15	empty
3	59	0.28	0.74	17	empty

Compared structures

6W9W · R80A PCNA mutant defective in BIR · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15873
Elsewhere: RCSB PDB 6W9W · PDBe 6W9W · UniProt P15873

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