MolNFT v1 · #167913 · protein
Crystal structure of human ppargamma ligand binding domain Y473E mutant in complex with darglitazone
6VZM: “Crystal structure of human ppargamma ligand binding domain Y473E mutant in complex with darglitazone”. X-ray diffraction, 1 ligand (GEV). MolNFT v1 #167913 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6VZM
- Type
- protein
- Length
- 508 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P37231
- Ligands
- GEV
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 253 | — | P37231 |
| B | — | protein | 255 | — | P37231 |
Ligands and binding sites
- GEV · (5Z)-5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl) propanoyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dione · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6VZM · Crystal structure of human PPARgamma ligand binding domain Y473E mutant in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37231
- Elsewhere: RCSB PDB 6VZM · PDBe 6VZM · UniProt P37231
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