MolNFT v1 · #16789 · protein
Structural view of a fungal toxin acting on a 14-3-3 regulatory complex
1O9D · 14-3-3-like protein C: “Structural view of a fungal toxin acting on a 14-3-3 regulatory complex”. X-ray diffraction, 2 pockets (best druggability 0.47). MolNFT v1 #16789 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1O9D
- Type
- protein
- Length
- 235 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 14-3-3-like protein C; Plasma membrane H+ ATPase
- UniProt
- P93343, Q40409
- Pockets
- 2 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 83% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 14-3-3-like protein C | protein | 230 | 84% helix, 0% strand | P93343 |
| P | Plasma membrane H+ ATPase | protein | 5 | 0% helix, 0% strand | Q40409 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 112 | 0.47 | 0.79 | 20 | empty |
| 2 | 56 | 0.35 | 0.78 | 14 | empty |
Interfaces
1 interface between chains.
- A–P · 529 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 1O9D · Structural view of a fungal toxin acting on a 14-3-3 regulatory complex · the same entry in another collection · chain A against A, TM-score 1.00
- P93343 · AlphaFold monomer V2.0 prediction for 14-3-3-like protein C (P93343) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P93343
- Every structure of UniProt Q40409
- Elsewhere: RCSB PDB 1O9D · PDBe 1O9D · UniProt P93343 · UniProt Q40409
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.