MolNFT v1 · #167763 · protein
Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (nmp) derivative 15C (N,N-diethyl-3',4'-dimethoxy-6-(1-methyl-5- oxopyrrolidin-3-yl)-[1,1'-biphenyl]-3-sulfonamide)
6VUJ: “Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (nmp) derivative 15C…”. X-ray diffraction, 2 ligands (RLY, NO3). MolNFT v1 #167763 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6VUJ
- Type
- protein
- Length
- 125 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O60885
- Ligands
- RLY, NO3
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 125 | — | O60885 |
Ligands and binding sites
- RLY · N,N-diethyl-3',4'-dimethoxy-6-[(3S)-1-methyl-5-oxopyrrolidin-3-yl][1,1'-biphenyl]-3-sulfonamide · ligand · chains A
- NO3 · Nitrate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6VUJ · Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative… · the same entry in another collection · chain A against A, TM-score 1.00
- O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60885
- Elsewhere: RCSB PDB 6VUJ · PDBe 6VUJ · UniProt O60885
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