MolNFT v1 · #16735 · protein

High resolution structure of siglec-7

1O7V · Sialic acid binding ig-like lectin 7: “High resolution structure of siglec-7”. X-ray diffraction, 3 ligands (MAN, NAG, BMA). MolNFT v1 #16735 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1O7V
Type: protein
Length: 127 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sialic acid binding ig-like lectin 7
UniProt: Q9Y286
Ligands: MAN, NAG, BMA

Structure

x-ray diffraction · 1 distinct chain · 9% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sialic acid binding ig-like lectin 7	protein	127	9% helix, 36% strand	Q9Y286

Ligands and binding sites

MAN · alpha-D-mannopyranose · sugar · 4 copies · chains A
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
BMA · beta-D-mannopyranose · sugar

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

1O7V · High resolution structure of Siglec-7 · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y286 · AlphaFold monomer V2.0 prediction for sialic acid-binding ig-like lectin 7 (Q9Y286) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y286
Elsewhere: RCSB PDB 1O7V · PDBe 1O7V · UniProt Q9Y286

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