MolNFT v1 · #167221 · protein

Pentadecameric pilq from pseudomonas aeruginosa

6VE4 · Fimbrial assembly protein pilq: “Pentadecameric pilq from pseudomonas aeruginosa”. Electron microscopy, 20 pockets (best druggability 0.87). MolNFT v1 #167221 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6VE4
Type: protein
Length: 4,560 residues
Chains: 15
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fimbrial assembly protein pilq
UniProt: P34750
Pockets: 20 · best druggability 0.87

Structure

electron microscopy · 1 distinct chain · 17% helix, 55% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O	Fimbrial assembly protein pilq	protein	304	17% helix, 55% strand	P34750

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1036	0.87	0.89	186	empty
2	1196	0.87	0.88	193	empty
3	1159	0.87	0.88	199	empty
4	553	0.85	0.91	119	empty
5	312	0.80	0.91	60	empty

Interfaces

15 interfaces between chains.

J–K · 1907 Å² buried · 36 hydrogen bonds · protein-protein
H–I · 1899 Å² buried · 36 hydrogen bonds · protein-protein
K–L · 1898 Å² buried · 35 hydrogen bonds · protein-protein
L–M · 1895 Å² buried · 35 hydrogen bonds · protein-protein
G–H · 1891 Å² buried · 36 hydrogen bonds · protein-protein

Compared structures

6VE4 · Pentadecameric PilQ from Pseudomonas aeruginosa · the same entry in another collection · chain O against O, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P34750
Elsewhere: RCSB PDB 6VE4 · PDBe 6VE4 · UniProt P34750

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