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MolNFT v1 · #167080 · RNA

Solution structure of the tau pre-mRNA exon 10 splicing regulatory element bound to mip

6VA4 · RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3'): “Solution structure of the tau pre-mRNA exon 10 splicing regulatory element bound to mip”. Solution nmr, 1 ligand (QSY). MolNFT v1 #167080 on GenesisL1: 3D structure, binding sites…

PDB
6VA4
Type
RNA
Length
21 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3'); RNA…
Ligands
QSY

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3')rna11——
BRNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3')rna10——

Ligands and binding sites

  • QSY · N-[3-(8-methoxy-4-oxo-4,5-dihydro-3H-pyrimido[5,4-b]indol-3-yl)propyl]-N-methylcyclohexanaminium · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 547 Ų buried · 51 hydrogen bonds · nucleic-nucleic

Compared structures

  • 6VA4 · Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MIP · the same entry in another collection · chain A against A, TM-score 1.00

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