MolNFT v1 · #167077 · RNA

Solution structure of the tau pre-mRNA exon 10 splicing regulatory element

6VA1 · RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3'): “Solution structure of the tau pre-mRNA exon 10 splicing regulatory element”. Solution nmr, 1 pocket (best druggability 0.24). MolNFT v1 #167077 on GenesisL1: 3D structure, binding…

PDB: 6VA1
Type: RNA
Length: 21 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3'); RNA…
Pockets: 1 · best druggability 0.24

Structure

solution nmr · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA (5'-R(CPCPGPGPCPAPGPUPGPUP*G)-3')	rna	11	—	—
B	RNA (5'-R(CPAPCPAPCPGPUPCPGPG)-3')	rna	10	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.24	0.71	12	empty

Interfaces

1 interface between chains.

A–B · 556 Å² buried · 49 hydrogen bonds · nucleic-nucleic

Compared structures

6VA1 · Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6VA1 · PDBe 6VA1

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