MolNFT v1 · #167020 · protein
Design, synthesis, and mechanism of fluorine-substituted cyclohexene analogues of gama-aminobutyric acid (GABA) as selective ornithine aminotransferase inactivators
6V8C: “Design, synthesis, and mechanism of fluorine-substituted cyclohexene analogues of gama-aminobutyric acid…”. X-ray diffraction, 2 ligands (PLP, QRM). MolNFT v1 #167020 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6V8C
- Type
- protein
- Length
- 1,212 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P04181
- Ligands
- PLP, QRM
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | — | protein | 404 | — | P04181 |
Ligands and binding sites
- PLP · Pyridoxal-5'-phosphate · ligand · 3 copies · chains A, B, C
- QRM · 3-aminocyclohexa-1,3-diene-1-carboxylic acid · ligand · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6V8C · Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of… · the same entry in another collection · chain A against A, TM-score 1.00
- P04181 · AlphaFold monomer V2.0 prediction for ornithine aminotransferase, mitochondrial (P04181) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04181
- Elsewhere: RCSB PDB 6V8C · PDBe 6V8C · UniProt P04181
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