MolNFT v1 · #166813 · protein
Structure of ndm-1 bound to QPX7728 at 1.05 a
6V1M · Metallo-beta-lactamase type 2: “Structure of ndm-1 bound to QPX7728 at 1.05 a”. X-ray diffraction, 2 ligands (QNA, ZN), 1 pocket (best druggability 0.42). MolNFT v1 #166813 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6V1M
- Type
- protein
- Length
- 229 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Metallo-beta-lactamase type 2
- EC
- 3.5.2.6
- UniProt
- C7C422
- Ligands
- QNA, ZN
- Pockets
- 1 · best druggability 0.42
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Metallo-beta-lactamase type 2 (EC 3.5.2.6) | protein | 229 | 27% helix, 31% strand | C7C422 |
Ligands and binding sites
- QNA · (1~{A}~{R},7~{B}~{S})-5-fluoranyl-2,2-bis(oxidanyl)-1~{A},7~{B}-dihydro-1~{H}-cyclopropa[c][1, 2]benzoxaborinine-4-carboxylic acid · ligand · chains A
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 123 | 0.42 | 0.76 | 19 | QNA |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C7C422
- Elsewhere: RCSB PDB 6V1M · PDBe 6V1M · UniProt C7C422
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.