MolNFT v1 · #166778 · protein
Lipophilic envelope-spanning tunnel B (letb), model 8
6V0J · Intermembrane transport protein yebt: “Lipophilic envelope-spanning tunnel B (letb), model 8”. Electron microscopy, 20 pockets (best druggability 0.73). MolNFT v1 #166778 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6V0J
- Type
- protein
- Length
- 2,010 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Intermembrane transport protein yebt
- UniProt
- P76272
- Pockets
- 20 · best druggability 0.73
Structure
electron microscopy · 1 distinct chain · 10% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Intermembrane transport protein yebt | protein | 335 | 10% helix, 38% strand | P76272 |
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 553 | 0.73 | 0.81 | 87 | empty |
| 2 | 701 | 0.70 | 0.77 | 80 | empty |
| 3 | 668 | 0.69 | 0.77 | 63 | empty |
| 4 | 598 | 0.68 | 0.78 | 51 | empty |
| 5 | 581 | 0.68 | 0.78 | 54 | empty |
Interfaces
6 interfaces between chains.
- E–F · 2120 Ų buried · 19 hydrogen bonds · protein-protein
- B–C · 2105 Ų buried · 19 hydrogen bonds · protein-protein
- A–F · 2097 Ų buried · 19 hydrogen bonds · protein-protein
- C–D · 2083 Ų buried · 17 hydrogen bonds · protein-protein
- A–B · 2080 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 6V0J · Lipophilic Envelope-spanning Tunnel B (LetB), Model 8 · the same entry in another collection · chain C against C, TM-score 1.00
- P76272 · AlphaFold monomer V2.0 prediction for intermembrane transport protein yebt (P76272) · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P76272
- Elsewhere: RCSB PDB 6V0J · PDBe 6V0J · UniProt P76272
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.