MolNFT v1 · #16676 · protein
Crystal structure of an ATP phosphoribosyltransferase
1O64: “Crystal structure of an ATP phosphoribosyltransferase”. X-ray diffraction, 1 ligand (PO4), 1 pocket (best druggability 0.67). MolNFT v1 #16676 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1O64
- Type
- protein
- Length
- 403 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATP phosphoribosyltransferase
- EC
- 2.4.2.17
- UniProt
- Q9X0D2
- Ligands
- PO4
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 34% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATP phosphoribosyltransferase (EC 2.4.2.17) | protein | 203 | 34% helix, 34% strand | Q9X0D2 |
| B | ATP phosphoribosyltransferase (EC 2.4.2.17) | protein | 200 | 34% helix, 37% strand | Q9X0D2 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 754 | 0.67 | 0.75 | 87 | PO4 |
Interfaces
1 interface between chains.
- A–B · 1113 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X0D2
- Elsewhere: RCSB PDB 1O64 · PDBe 1O64 · UniProt Q9X0D2
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