MolNFT v1 · #166606 · protein
Crystal structure of BCL-xl bound to compound 13: (R)-2-(3-([1,1'- biphenyl]-4-carbonyl)-3-(4-METHYLBENZYL)UREIDO)-3-(((3R,5R,7R)- adamantan-1-YLMETHYL)SULFONYL)PROPANOIC acid
6UVG: “Crystal structure of BCL-xl bound to compound 13: (R)-2-(3-([1,1'…”. X-ray diffraction, 2 ligands (QHP, SO4). MolNFT v1 #166606 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6UVG
- Type
- protein
- Length
- 1,684 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q07817
- Ligands
- QHP, SO4
Structure
x-ray diffraction · 11 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 145 | — | Q07817 |
| B | — | protein | 144 | — | Q07817 |
| C | — | protein | 138 | — | Q07817 |
| D | — | protein | 140 | — | Q07817 |
| E | — | protein | 140 | — | Q07817 |
| F | — | protein | 141 | — | Q07817 |
| G | — | protein | 141 | — | Q07817 |
| H, K | — | protein | 142 | — | Q07817 |
| I | — | protein | 138 | — | Q07817 |
| J | — | protein | 133 | — | Q07817 |
| L | — | protein | 140 | — | Q07817 |
Ligands and binding sites
- QHP · (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic acid · ligand · 12 copies · chains A, B, C, K, D, E, F, G, H, I, J, L
- SO4 · Sulfate ion · ion · 8 copies · chains A, B, G, H, C, D, I, J, K, L
- EDO · 1,2-ethanediol · additive · 5 copies · chains A, E, G, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6UVG · Crystal structure of BCL-XL bound to compound 13… · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07817
- Elsewhere: RCSB PDB 6UVG · PDBe 6UVG · UniProt Q07817
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