MolNFT v1 · #166604 · protein

Crystal structure of BCL-xl bound to compound 7: (R)-3-(benzylthio)-2- (3-(4-chloro-[1,1':2',1'':3'',1'''-quaterphenyl]-4'''-carbonyl)-3-(4- METHYLBENZYL)UREIDO)PROPANOIC acid

6UVE: “Crystal structure of BCL-xl bound to compound 7: (R)-3-(benzylthio)-2…”. X-ray diffraction, 1 ligand (QHV). MolNFT v1 #166604 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6UVE
Type: protein
Length: 415 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q07817
Ligands: QHV

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	133	—	Q07817
B	—	protein	134	—	Q07817
C	—	protein	148	—	Q07817

Ligands and binding sites

QHV · (R)-3-(benzylthio)-2-(3-(4-chloro-[1,1':2',1'':3'', 1'''-quaterphenyl]-4'''-carbonyl)-3-(4-methylbenzyl) ureido)propanoic acid · ligand · 3 copies · chains A, B, C
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6UVE · Crystal structure of BCL-XL bound to compound 7… · the same entry in another collection · chain A against A, TM-score 1.00
Q07817 · AlphaFold monomer V2.0 prediction for BCL-2-like protein 1 (Q07817) · a predicted model of the same protein · chain B against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q07817
Elsewhere: RCSB PDB 6UVE · PDBe 6UVE · UniProt Q07817

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.