MolNFT v1 · #166389 · protein

1.2 ångström resolution crystal structure of cbs domains of transcriptional regulator from streptococcus pneumoniae

6UOF · Transcriptional regulator containing cbs domains: “1.2 ångström resolution crystal structure of cbs domains of transcriptional regulator from streptococcus…”. X-ray diffraction, 2 ligands (NA, CL), 1 pocket (best druggability 0.40).…

PDB: 6UOF
Type: protein
Length: 119 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional regulator containing cbs domains
UniProt: Q8DPV2
Ligands: NA, CL
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator containing cbs domains	protein	119	36% helix, 27% strand	Q8DPV2

Ligands and binding sites

NA · Sodium ion · metal · chains A
CL · Chloride ion · ion · chains A
PEG · Di(hydroxyethyl)ether · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.40	0.78	18	CL

Modifications

Observed in the structure: 5 modified (engineered).

Compared structures

6UOF · 1.2 Angstrom Resolution Crystal Structure of CBS Domains of Transcriptional Regulator… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8DPV2
Elsewhere: RCSB PDB 6UOF · PDBe 6UOF · UniProt Q8DPV2

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