MolNFT v1 · #166369 · protein

Kinase domain of ALK2-K492A/K493A with ldn-193189

6UNS: “Kinase domain of ALK2-K492A/K493A with ldn-193189”. X-ray diffraction, 1 ligand (LDN). MolNFT v1 #166369 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6UNS
Type: protein
Length: 578 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q04771
Ligands: LDN

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	288	—	Q04771
B	—	protein	290	—	Q04771

Ligands and binding sites

LDN · 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6UNS · Kinase domain of ALK2-K492A/K493A with LDN-193189 · the same entry in another collection · chain A against A, TM-score 1.00
Q04771 · AlphaFold monomer V2.0 prediction for activin receptor type-1 (Q04771) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q04771
Elsewhere: RCSB PDB 6UNS · PDBe 6UNS · UniProt Q04771

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