MolNFT v1 · #166251 · protein
Crystal structure of human gac in complex with inhibitor UPGL00012
6UKB: “Crystal structure of human gac in complex with inhibitor UPGL00012”. X-ray diffraction, 1 ligand (Q9V). MolNFT v1 #166251 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6UKB
- Type
- protein
- Length
- 1,638 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O94925
- Ligands
- Q9V
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 409 | — | O94925 |
| C, D | — | protein | 410 | — | O94925 |
Ligands and binding sites
- Q9V · N-[5-(4-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]oxy}piperidin-1-yl)-1,3,4-thiadiazol-2-yl]acetamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6UKB · Crystal structure of human GAC in complex with inhibitor UPGL00012 · the same entry in another collection · chain D against D, TM-score 1.00
- O94925 · AlphaFold monomer V2.0 prediction for glutaminase kidney isoform, mitochondrial (O94925) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O94925
- Elsewhere: RCSB PDB 6UKB · PDBe 6UKB · UniProt O94925
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.