MolNFT v1 · #166046 · protein
Structure of rabies sad-B19 L-P complex from cryo-EM
6UEB · Large structural protein: “Structure of rabies sad-B19 L-P complex from cryo-EM”. Electron microscopy, 1 ligand (ZN), 20 pockets (best druggability 0.80). MolNFT v1 #166046 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6UEB
- Type
- protein
- Length
- 2,141 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Large structural protein; PHOSPHOPROTEIN,PHOSPHOPROTEIN
- EC
- 2.7.7.48, 2.1.1.56, 2.7.7.88, 2.1.1.296
- UniProt
- P16289, P16286
- Ligands
- ZN
- Pockets
- 20 · best druggability 0.80
Structure
electron microscopy · 2 distinct chains · 45% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Large structural protein (EC 2.7.7.48, 2.1.1.56, 2.7.7.88, 2.1.1.296) | protein | 2099 | 46% helix, 7% strand | P16289 |
| B | PHOSPHOPROTEIN,PHOSPHOPROTEIN | protein | 42 | 0% helix, 5% strand | P16286 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 19 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 762 | 0.80 | 0.84 | 122 | empty |
| 2 | 672 | 0.80 | 0.85 | 75 | empty |
| 3 | 536 | 0.80 | 0.86 | 46 | empty |
| 4 | 543 | 0.77 | 0.84 | 66 | empty |
| 5 | 616 | 0.77 | 0.82 | 79 | empty |
Interfaces
1 interface between chains.
- A–B · 2123 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 6UEB · Structure of Rabies SAD-B19 L-P complex from cryo-EM · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16289
- Every structure of UniProt P16286
- Elsewhere: RCSB PDB 6UEB · PDBe 6UEB · UniProt P16289 · UniProt P16286
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