MolNFT v1 · #165921 · protein
Lahsb - C-terminal methyltransferase involved in ripp biosynthesis
6UAK · SAM dependent methyltransferase lahsb: “Lahsb - C-terminal methyltransferase involved in ripp biosynthesis”. X-ray diffraction, 1 ligand (SAH), 2 pockets (best druggability 0.80). MolNFT v1 #165921 on GenesisL1: 3D structure…
- PDB
- 6UAK
- Type
- protein
- Length
- 297 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SAM dependent methyltransferase lahsb
- UniProt
- A0A3D0LE54
- Ligands
- SAH
- Pockets
- 2 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SAM dependent methyltransferase lahsb | protein | 297 | 44% helix, 22% strand | A0A3D0LE54 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1110 | 0.80 | 0.81 | 90 | SAH |
| 2 | 225 | 0.53 | 0.77 | 30 | empty |
Compared structures
- 6UAK · LahSb - C-terminal methyltransferase involved in RiPP biosynthesis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A3D0LE54
- Elsewhere: RCSB PDB 6UAK · PDBe 6UAK · UniProt A0A3D0LE54
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