MolNFT v1 · #165859 · protein

BRD4-BD1 in complex with the cyclic peptide 3.2_1

6U8M: “BRD4-BD1 in complex with the cyclic peptide 3.2_1”. X-ray diffraction, 2 ligands (ACE, NH2). MolNFT v1 #165859 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6U8M
Type: protein
Length: 252 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O60885
Ligands: ACE, NH2

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	125	—	O60885
B	—	protein	110	—	O60885
C	—	protein	17	—	—

Ligands and binding sites

ACE · Acetyl group · ligand · chains B, C
NH2 · Amino group · ion · chains C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6U8M · BRD4-BD1 in complex with the cyclic peptide 3.2_1 · the same entry in another collection · chain A against A, TM-score 1.00
O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O60885
Elsewhere: RCSB PDB 6U8M · PDBe 6U8M · UniProt O60885

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