MolNFT v1 · #165661 · protein

Braf-MEK complex with AMP-pcp bound to braf

6U2G: “Braf-MEK complex with AMP-pcp bound to braf”. X-ray diffraction, 3 ligands (ACP, MG, SO4). MolNFT v1 #165661 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6U2G
Type: protein
Length: 573 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q02750, P15056
Ligands: ACP, MG, SO4

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	309	—	Q02750
B	—	protein	264	—	P15056

Ligands and binding sites

ACP · Phosphomethylphosphonic acid adenylate ester · ligand · 2 copies · chains A, B
MG · Magnesium ion · metal · 2 copies · chains A, B
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6U2G · BRAF-MEK complex with AMP-PCP bound to BRAF · the same entry in another collection · chain A against A, TM-score 1.00
P15056 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase B-RAF (P15056) · a predicted model of the same protein · chain B against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q02750
Every structure of UniProt P15056
Elsewhere: RCSB PDB 6U2G · PDBe 6U2G · UniProt Q02750 · UniProt P15056

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