MolNFT v1 · #165651 · protein

AAV8 human HEK293-produced, empty capsid

6U20 · Capsid protein: “AAV8 human HEK293-produced, empty capsid”. Electron microscopy, 7 pockets (best druggability 0.56). MolNFT v1 #165651 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6U20
Type: protein
Length: 519 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Capsid protein
UniProt: Q8JQF8
Pockets: 7 · best druggability 0.56

Structure

electron microscopy · 1 distinct chain · 6% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Capsid protein	protein	519	6% helix, 31% strand	Q8JQF8

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	286	0.56	0.76	41	empty
2	313	0.56	0.75	36	empty
3	115	0.42	0.76	22	empty
4	143	0.40	0.74	25	empty
5	72	0.40	0.79	20	empty

Compared structures

6U20 · AAV8 human HEK293-produced, empty capsid · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8JQF8
Elsewhere: RCSB PDB 6U20 · PDBe 6U20 · UniProt Q8JQF8

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