MolNFT v1 · #165582 · protein
Crystal structure of tetrahymena thermophila lipin phosphatidic acid phosphatase with magnesium
6TZZ · Nuclear elongation and deformation protein: “Crystal structure of tetrahymena thermophila lipin phosphatidic acid phosphatase with magnesium”. X-ray diffraction, 1 ligand (MG), 3 pockets (best druggability 0.65). MolNFT v1 #165582…
- PDB
- 6TZZ
- Type
- protein
- Length
- 538 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nuclear elongation and deformation protein
- UniProt
- I7MFJ3
- Ligands
- MG
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 2 distinct chains · 23% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear elongation and deformation protein | protein | 277 | 23% helix, 34% strand | I7MFJ3 |
| B | Nuclear elongation and deformation protein | protein | 261 | 23% helix, 36% strand | I7MFJ3 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 95 | 0.65 | 0.90 | 23 | empty |
| 2 | 101 | 0.52 | 0.82 | 21 | empty |
| 3 | 66 | 0.28 | 0.73 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 258 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 6TZZ · Crystal Structure of Tetrahymena Thermophila Lipin Phosphatidic Acid Phosphatase with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I7MFJ3
- Elsewhere: RCSB PDB 6TZZ · PDBe 6TZZ · UniProt I7MFJ3
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