MolNFT v1 · #1654 · protein

PARVALBUMIN

1B8C · Protein (parvalbumin): “PARVALBUMIN”. X-ray diffraction, 1 ligand (MG), 2 pockets (best druggability 0.59). MolNFT v1 #1654 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1B8C
Type: protein
Length: 216 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (parvalbumin)
UniProt: P02618
Ligands: MG
Pockets: 2 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein (parvalbumin)	protein	108	53% helix, 4% strand	P02618

Ligands and binding sites

MG · Magnesium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	133	0.59	0.84	27	empty
2	191	0.51	0.77	25	empty

Interfaces

1 interface between chains.

A–B · 306 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

1B8C · PARVALBUMIN · the same entry in another collection · chain A against A, TM-score 1.00
P02618 · AlphaFold monomer V2.0 prediction for parvalbumin beta (P02618) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02618
Elsewhere: RCSB PDB 1B8C · PDBe 1B8C · UniProt P02618

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