MolNFT v1 · #165282 · protein

Crystal structures of fniii domain one through four of the human leucocyte common antigen-related protein ( lar)

6TPW · Receptor-type tyrosine-protein phosphatase F: “Crystal structures of fniii domain one through four of the human leucocyte common antigen-related protein (…”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.43).…

PDB: 6TPW
Type: protein
Length: 375 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Receptor-type tyrosine-protein phosphatase F
EC: 3.1.3.48
UniProt: P10586
Ligands: SO4
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48)	protein	375	2% helix, 48% strand	P10586

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.43	0.79	20	empty

Compared structures

6TPW · Crystal structures of FNIII domain one through four of the human leucocyte common… · the same entry in another collection · chain A against A, TM-score 1.00
P10586 · AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase F… · a predicted model of the same protein · chain A against A, TM-score 0.50

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10586
Elsewhere: RCSB PDB 6TPW · PDBe 6TPW · UniProt P10586

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