MolNFT v1 · #165206 · protein

Structure of FANCD2 in complex with fanci

6TNG · Uncharacterized protein: “Structure of FANCD2 in complex with fanci”. Electron microscopy, 19 pockets (best druggability 0.65). MolNFT v1 #165206 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6TNG
Type: protein
Length: 2,060 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein; Fanconi anemia complementation group I
UniProt: F1NP22, B0I564
Pockets: 19 · best druggability 0.65

Structure

electron microscopy · 2 distinct chains · 56% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein	protein	1027	57% helix, 0% strand	F1NP22
B	Fanconi anemia complementation group I	protein	1033	55% helix, 0% strand	B0I564

Pockets

19 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	974	0.65	0.73	148	empty
2	803	0.64	0.73	98	empty
3	611	0.61	0.74	81	empty
4	600	0.58	0.72	92	empty
5	450	0.53	0.72	70	empty

Interfaces

1 interface between chains.

A–B · 66 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

6TNG · Structure of FANCD2 in complex with FANCI · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F1NP22
Every structure of UniProt B0I564
Elsewhere: RCSB PDB 6TNG · PDBe 6TNG · UniProt F1NP22 · UniProt B0I564

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