MolNFT v1 · #165191 · protein
Structure of the chaperonin GP146 from the bacteriophage el (pseudomonas aeruginosa) in the apo state
6TMV · Putative groel-like chaperonine protein: “Structure of the chaperonin GP146 from the bacteriophage el (pseudomonas aeruginosa) in the apo state”. Electron microscopy, 20 pockets (best druggability 0.80). MolNFT v1 #165191 on…
- PDB
- 6TMV
- Type
- protein
- Length
- 7,604 residues
- Chains
- 14
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative groel-like chaperonine protein
- UniProt
- Q2Z0T5
- Pockets
- 20 · best druggability 0.80
Structure
electron microscopy · 2 distinct chains · 49% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, E, H, J, L | Putative groel-like chaperonine protein | protein | 546 | 49% helix, 15% strand | Q2Z0T5 |
| B, D, F, G, I, K, M, N | Putative groel-like chaperonine protein | protein | 541 | 49% helix, 16% strand | Q2Z0T5 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 959 | 0.80 | 0.82 | 91 | empty |
| 2 | 838 | 0.80 | 0.83 | 81 | empty |
| 3 | 1013 | 0.79 | 0.81 | 79 | empty |
| 4 | 930 | 0.79 | 0.81 | 78 | empty |
| 5 | 1127 | 0.79 | 0.80 | 97 | empty |
Interfaces
28 interfaces between chains.
- E–F · 1492 Ų buried · 13 hydrogen bonds · protein-protein
- L–M · 1482 Ų buried · 13 hydrogen bonds · protein-protein
- H–I · 1465 Ų buried · 13 hydrogen bonds · protein-protein
- A–B · 1458 Ų buried · 13 hydrogen bonds · protein-protein
- J–K · 1437 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 6TMV · Structure of the chaperonin gp146 from the bacteriophage EL (Pseudomonas aeruginosa) in… · the same entry in another collection · chain E against E, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2Z0T5
- Elsewhere: RCSB PDB 6TMV · PDBe 6TMV · UniProt Q2Z0T5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.