MolNFT v1 · #165073 · protein
Noe based model of hvdac-1 bound to beta-NADH in detergent micelles
6TIR · Voltage-dependent anion-selective channel protein 1: “Noe based model of hvdac-1 bound to beta-NADH in detergent micelles”. Solution nmr, 1 ligand (NAI), 4 pockets (best druggability 0.55). MolNFT v1 #165073 on GenesisL1: 3D…
- PDB
- 6TIR
- Type
- protein
- Length
- 285 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Voltage-dependent anion-selective channel protein 1
- UniProt
- P21796
- Ligands
- NAI
- Pockets
- 4 · best druggability 0.55
Structure
solution nmr · 1 distinct chain · 4% helix, 63% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Voltage-dependent anion-selective channel protein 1 | protein | 285 | 4% helix, 63% strand | P21796 |
Ligands and binding sites
- NAI · 1,4-dihydronicotinamide adenine dinucleotide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 211 | 0.55 | 0.78 | 34 | empty |
| 2 | 330 | 0.53 | 0.74 | 36 | empty |
| 3 | 133 | 0.49 | 0.79 | 25 | empty |
| 4 | 95 | 0.47 | 0.81 | 26 | empty |
Compared structures
- 6TIR · NOE based model of hVDAC-1 bound to beta-NADH in detergent micelles · the same entry in another collection · chain A against A, TM-score 1.00
- P21796 · AlphaFold monomer V2.0 prediction for voltage-dependent anion- selective channel protein… · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21796
- Elsewhere: RCSB PDB 6TIR · PDBe 6TIR · UniProt P21796
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.