MolNFT v1 · #165072 · protein

Refined solution NMR structure of hvdac-1 in detergent micelles

6TIQ · Voltage-dependent anion-selective channel protein 1: “Refined solution NMR structure of hvdac-1 in detergent micelles”. Solution nmr, 3 pockets (best druggability 0.63). MolNFT v1 #165072 on GenesisL1: 3D structure, binding sites…

PDB: 6TIQ
Type: protein
Length: 285 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Voltage-dependent anion-selective channel protein 1
UniProt: P21796
Pockets: 3 · best druggability 0.63

Structure

solution nmr · 1 distinct chain · 5% helix, 65% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Voltage-dependent anion-selective channel protein 1	protein	285	5% helix, 65% strand	P21796

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	433	0.63	0.77	53	empty
2	402	0.61	0.77	46	empty
3	56	0.31	0.76	19	empty

Compared structures

6TIQ · Refined solution NMR structure of hVDAC-1 in detergent micelles · the same entry in another collection · chain A against A, TM-score 1.00
P21796 · AlphaFold monomer V2.0 prediction for voltage-dependent anion- selective channel protein… · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21796
Elsewhere: RCSB PDB 6TIQ · PDBe 6TIQ · UniProt P21796

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