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MolNFT v1 · #165003 · protein

Cryo-EM structure of NADH reduced form of NAD+-dependent formate dehydrogenase from rhodobacter capsulatus

6TG9: “Cryo-EM structure of NADH reduced form of NAD+-dependent formate dehydrogenase from rhodobacter capsulatus”. Electron microscopy, 7 ligands (SF4, MGD, FES). MolNFT v1 #165003 on GenesisL1: 3D structure, binding sites and pockets in…

PDB
6TG9
Type
protein
Length
3,318 residues
Chains
8
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0A0E2PAE3, A0A0E2P9P2, A0A0E2PAI9, A0A0E2P9Z0
Ligands
SF4, MGD, FES, FMN, NAI, 6MO, H2S

Structure

electron microscopy · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, E—protein949—A0A0E2PAE3
B, F—protein493—A0A0E2P9P2
G, C—protein148—A0A0E2PAI9
D, H—protein69—A0A0E2P9Z0

Ligands and binding sites

  • SF4 · Iron/sulfur cluster · ligand · 10 copies · chains A, B, E, F
  • MGD · 2-amino-5,6-dimercapto-7-methyl-3,7,8A,9-tetrahydro-8-oxa-1,3,9,10-tetraaza-anthracen-4-one guanosine dinucleotide · ligand · 4 copies · chains A, E
  • FES · Fe2/s2 (inorganic) cluster · ligand · 4 copies · chains A, G, E, C
  • FMN · Flavin mononucleotide · ligand · 2 copies · chains B, F
  • NAI · 1,4-dihydronicotinamide adenine dinucleotide · ligand · 2 copies · chains A, B, E, F
  • 6MO · Molybdenum(vi) ion · metal · 2 copies · chains A, E
  • H2S · Hydrosulfuric acid · ion · 2 copies · chains A, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6TG9 · Cryo-EM Structure of NADH reduced form of NAD+-dependent Formate Dehydrogenase from… · the same entry in another collection · chain A against A, TM-score 1.00

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