MolNFT v1 · #16470 · protein

Wild-type penicillin-binding protein 5 from E. COLI modified by beta-mercaptoethanol

1NZU: “Wild-type penicillin-binding protein 5 from E. COLI modified by beta-mercaptoethanol”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #16470 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1NZU
Type: protein
Length: 347 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Penicillin-binding protein 5
EC: 3.4.16.4
UniProt: P04287
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Penicillin-binding protein 5 (EC 3.4.16.4)	protein	347	30% helix, 33% strand	P04287

Ligands and binding sites

BME · Beta-mercaptoethanol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.30	0.74	23	empty

Modifications

Observed in the structure: 1 covalent (additive adduct).

Compared structures

1NZU · Wild-type penicillin-binding protein 5 from E. coli modified by beta-mercaptoethanol · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04287
Elsewhere: RCSB PDB 1NZU · PDBe 1NZU · UniProt P04287

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