MolNFT v1 · #164695 · protein

A model of the eiav ca-sp hexamer (C6) from gag-deltama spheres assembled at PH6

6T64 · Gag polyprotein: “A model of the eiav ca-sp hexamer (C6) from gag-deltama spheres assembled at PH6”. Electron microscopy, 5 pockets (best druggability 0.74). MolNFT v1 #164695 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6T64
Type: protein
Length: 651 residues
Chains: 3
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gag polyprotein
UniProt: P69730
Pockets: 5 · best druggability 0.74

Structure

electron microscopy · 1 distinct chain · 59% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Gag polyprotein	protein	217	59% helix, 0% strand	P69730

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	534	0.74	0.82	65	empty
2	868	0.73	0.78	96	empty
3	356	0.64	0.79	44	empty
4	455	0.63	0.77	37	empty
5	61	0.30	0.75	13	empty

Interfaces

3 interfaces between chains.

A–C · 1031 Å² buried · 4 hydrogen bonds · protein-protein
B–C · 826 Å² buried · 1 hydrogen bond · protein-protein
A–B · 522 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

6T64 · A model of the EIAV CA-SP hexamer (C6) from Gag-deltaMA spheres assembled at pH6 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P69730
Elsewhere: RCSB PDB 6T64 · PDBe 6T64 · UniProt P69730

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