MolNFT v1 · #164427 · protein

Crystal structure of the accessory translocation ATPase, SECA2, from clostridium difficile

6SXH · Protein translocase subunit seca 2: “Crystal structure of the accessory translocation ATPase, SECA2, from clostridium difficile”. X-ray diffraction, 9 pockets (best druggability 0.77). MolNFT v1 #164427 on GenesisL1: 3D structure…

PDB: 6SXH
Type: protein
Length: 769 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein translocase subunit seca 2
UniProt: Q183M9
Pockets: 9 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 57% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein translocase subunit seca 2	protein	769	57% helix, 12% strand	Q183M9

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	975	0.77	0.79	84	empty
2	488	0.72	0.81	76	empty
3	242	0.64	0.82	39	empty
4	144	0.61	0.85	20	empty
5	122	0.51	0.80	19	empty

Compared structures

6SXH · Crystal structure of the accessory translocation ATPase, SecA2, from Clostridium difficile · the same entry in another collection · chain A against A, TM-score 1.00
Q183M9 · AlphaFold monomer V2.0 prediction for protein translocase subunit seca 2 (Q183M9) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q183M9
Elsewhere: RCSB PDB 6SXH · PDBe 6SXH · UniProt Q183M9

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