MolNFT v1 · #164082 · protein
A. thaliana serine hydroxymethyltransferase isoform 4 (ATSHMT4) in complex with methotrexate
6SMR: “A. thaliana serine hydroxymethyltransferase isoform 4 (ATSHMT4) in complex with methotrexate”. X-ray diffraction. MolNFT v1 #164082 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6SMR
- Type
- protein
- Length
- 1,894 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O23254
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 475 | — | O23254 |
| B | — | protein | 474 | — | O23254 |
| C | — | protein | 472 | — | O23254 |
| D | — | protein | 473 | — | O23254 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 9 copies · chains A, D, B, C
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- O23254 · AlphaFold monomer V2.0 prediction for serine hydroxymethyltransferase 4 (O23254) · a predicted model of the same protein · chain D against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O23254
- Elsewhere: RCSB PDB 6SMR · PDBe 6SMR · UniProt O23254
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