MolNFT v1 · #164013 · protein
The tle hydrolase bound to the ttr domain of the vgrg spike of the type 6 secretion system
6SKI · Putative type VI secretion protein: “The tle hydrolase bound to the ttr domain of the vgrg spike of the type 6 secretion system”. Electron microscopy, 6 pockets (best druggability 0.74). MolNFT v1 #164013 on GenesisL1: 3D structure…
- PDB
- 6SKI
- Type
- protein
- Length
- 569 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative type VI secretion protein
- UniProt
- A0A377LA80, A0A3W2RZ19
- Pockets
- 6 · best druggability 0.74
Structure
electron microscopy · 2 distinct chains · 28% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| F | Putative type VI secretion protein | protein | 521 | 30% helix, 25% strand | A0A377LA80 |
| A | Putative type VI secretion protein | protein | 48 | 0% helix, 46% strand | A0A3W2RZ19 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 481 | 0.74 | 0.83 | 45 | empty |
| 2 | 162 | 0.54 | 0.80 | 38 | empty |
| 3 | 172 | 0.46 | 0.75 | 30 | empty |
| 4 | 132 | 0.41 | 0.74 | 31 | empty |
| 5 | 70 | 0.35 | 0.77 | 15 | empty |
Interfaces
1 interface between chains.
- F–A · 1349 Ų buried · 29 hydrogen bonds · protein-protein
Compared structures
- 6SKI · The Tle hydrolase bound to the TTR domain of the VgrG spike of the Type 6 secretion system · the same entry in another collection · chain F against F, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A377LA80
- Every structure of UniProt A0A3W2RZ19
- Elsewhere: RCSB PDB 6SKI · PDBe 6SKI · UniProt A0A377LA80 · UniProt A0A3W2RZ19
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