MolNFT v1 · #163908 · protein

Diffraction data for ROAB13 crystal co-crystallised with piydin and its ROAB13 structure

6SHG · Antibody ROAB13 heavy chain: “Diffraction data for ROAB13 crystal co-crystallised with piydin and its ROAB13 structure”. X-ray diffraction, 7 pockets (best druggability 0.62). MolNFT v1 #163908 on GenesisL1: 3D structure, binding…

PDB: 6SHG
Type: protein
Length: 432 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Antibody ROAB13 heavy chain; Antibody ROAB13 light chain
Pockets: 7 · best druggability 0.62

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
H	Antibody ROAB13 heavy chain	protein	218	3% helix, 50% strand	—
L	Antibody ROAB13 light chain	protein	214	3% helix, 39% strand	—

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	515	0.62	0.75	50	empty
2	173	0.54	0.79	26	empty
3	74	0.44	0.81	19	empty
4	79	0.36	0.76	13	empty
5	80	0.35	0.76	17	empty

Interfaces

1 interface between chains.

H–L · 1851 Å² buried · 20 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

6SHG · Diffraction data for RoAb13 crystal co-crystallised with PIYDIN and its RoAb13 structure · the same entry in another collection · chain H against H, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6SHG · PDBe 6SHG

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