MolNFT v1 · #163839 · protein

Lemur tyrosine kinase 3 (LMTK3)

6SEQ · SERINE/THREONINE-protein kinase LMTK3: “Lemur tyrosine kinase 3 (LMTK3)”. X-ray diffraction, 2 pockets (best druggability 0.64). MolNFT v1 #163839 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6SEQ
Type: protein
Length: 278 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SERINE/THREONINE-protein kinase LMTK3
EC: 2.7.11.1
UniProt: Q96Q04
Pockets: 2 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein kinase LMTK3 (EC 2.7.11.1)	protein	278	39% helix, 18% strand	Q96Q04

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	371	0.64	0.78	44	empty
2	79	0.41	0.79	20	empty

Compared structures

6SEQ · Lemur tyrosine kinase 3 (LMTK3) · the same entry in another collection · chain A against A, TM-score 1.00
Q96Q04 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase LMTK3 (Q96Q04) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96Q04
Elsewhere: RCSB PDB 6SEQ · PDBe 6SEQ · UniProt Q96Q04

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